Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459056 | 0.89 | KDM4E (0.33) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5228868 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5229060 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL7254084 | 0.71 | ALDH1A1 (0.33) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL12555615 | 0.62 | — | — | |
| SCHEMBL7946227 | 0.61 | PDE4B (0.36) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5722790 | 0.58 | MAPT (0.51) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5723212 | 0.57 | KDM4E (0.47) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5000921 | 0.57 | MAPK1 (0.35) | KDM4EALDH1A1LMNA | |
| SCHEMBL7951450 | 0.56 | GAA (0.34) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197393-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES | WITSCHEL MATTHIAS | 2007-08-23 | — | — | US | disclosed |
| US-7115545-B1 | Tricyclic benzoylpyrazole derivatives used as a herbicide | BASF AKTIENGESELLSCHAFT (DE) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197393-A1 | TRICYCLIC BENZOYLPYRAZOLE DERIVATIVES | CBR3, CBR1, KAT8 | KDM4E 2750/4885ALDH1A1 4069/4885LMNA 3722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.