Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455502 | 0.92 | BDKRB1 (0.37) | DPP4DPP8DPP9KDM4ACTSS | |
| SCHEMBL5443078 | 0.87 | DPP4 (0.54) | DPP4DPP8DPP9KDM4A | |
| SCHEMBL5443593 | 0.87 | DPP4 (0.54) | DPP4DPP8DPP9 | |
| SCHEMBL5445504 | 0.85 | DPP4 (0.64) | DPP4DPP8DPP9 | |
| SCHEMBL5456858 | 0.84 | DPP4 (0.55) | DPP4DPP8DPP9 | |
| SCHEMBL3897103 | 0.83 | DPP4 (0.47) | DPP4CYP3A4SCN9ASCN10A | |
| SCHEMBL5739337 | 0.82 | DPP4 (0.53) | DPP4DPP8DPP9POLBMAPK1 | |
| SCHEMBL5445312 | 0.80 | DPP4 (0.46) | DPP4DPP8DPP9KDM4A | |
| SCHEMBL3907842 | 0.79 | DPP4 (0.43) | DPP4KDM4ACYP3A4SCN9ASCN10A | |
| Hydrochloric Acid SCHEMBL5443567 | 0.79 | DPP4 (0.69) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | DPP4 1/4885DPP8 8/4885DPP9 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.