Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5820914 | 0.93 | KCNH2 (0.40) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5461882 | 0.92 | KCNH2 (0.43) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5465125 | 0.90 | JAK2 (0.37) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5450719 | 0.87 | KCNH2 (0.48) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5466811 | 0.86 | KCNH2 (0.40) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5450731 | 0.85 | KCNH2 (0.44) | KCNH2CYP3A4 | |
| SCHEMBL5460676 | 0.85 | KCNH2 (0.44) | KCNH2CYP3A4 | |
| SCHEMBL5460508 | 0.85 | KCNH2 (0.42) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5823865 | 0.84 | KCNH2 (0.43) | KCNH2JAK2JAK1TYK2JAK3 | |
| SCHEMBL5453164 | 0.84 | KCNH2 (0.41) | KCNH2JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191333-A1 | Antibacterial agents | WARNER LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | claimed |
| US-20070191333-A1 | Antibacterial agents | WARNER LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |
| US-20070191333-A1 | Antibacterial agents | WARNER LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191333-A1 | Antibacterial agents | MRPL21, RPN2, FBL | KCNH2 2633/4885JAK2 4764/4885JAK1 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.