Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5450976 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5449258 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5453414 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5459333 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5459864 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5455722 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5453085 | 0.99 | SLC9A1 (0.41) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5447171 | 0.96 | MEN1 (0.40) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5457443 | 0.89 | TLR8 (0.43) | TLR8SLC9A1NPC1RAB9AATM | |
| SCHEMBL5460407 | 0.88 | SLC9A1 (0.43) | TLR8SLC9A1NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796193-B2 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20070155635-A1 | Refrigerating machine oil compositions | NIPPON OIL CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |