Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RPS6KA2 | Q15349 | 3/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14388704 | 1.00 | NAMPT (0.48) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL5332204 | 0.99 | NAMPT (0.49) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL12256159 | 0.89 | NAMPT (0.48) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL14361885 | 0.89 | NAMPT (0.40) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL13952739 | 0.87 | NAMPT (0.49) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL30125632 | 0.87 | NAMPT (0.46) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL5331486 | 0.87 | NAMPT (0.46) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL5331221 | 0.86 | NAMPT (0.46) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL6431430 | 0.86 | NAMPT (0.48) | NAMPTROCK2ROCK1GRM1GRM4 | |
| SCHEMBL6576406 | 0.85 | NAMPT (0.46) | NAMPTROCK2ROCK1GRM1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |