Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | GAA | P10253 | 6/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439501 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8439096 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8442878 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8443341 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8440594 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8391699 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8438232 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL1872089 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8443237 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL8441562 | 0.86 | LMNA (0.65) | CYP1A2CYP2C9CYP2C19KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |