SCHEMBL5456201

SCHEMBL5456201

CC(=O)NC[C@@H]1CN(c2ccc(-c3cnc(OC(N)=O)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.61
CALML3 P27482 5/20 0.56
MAOB P27338 3/20 0.56
LMNA P02545 1/20 0.56
PTGS1 P23219 1/20 0.56
SDHA P31040 1/20 0.56
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6793510 0.91 MAOA (0.64) MAOACALML3MAOBLMNAPTGS1
SCHEMBL2897655 0.89 MAOA (0.67) MAOACALML3MAOBLMNAPTGS1
SCHEMBL6797685 0.89 MAOA (0.66) MAOACALML3MAOBLMNAPTGS1
SCHEMBL5520094 0.85 MAOA (0.62) MAOACALML3MAOBLMNAPTGS1
SCHEMBL6797993 0.85 MAOA (0.62) MAOACALML3MAOBLMNAPTGS1
SCHEMBL6614774 0.85 MAOA (0.66) MAOACALML3MAOBLMNAPTGS1
SCHEMBL5173481 0.84 MAOA (0.63) MAOACALML3MAOBLMNAPTGS1
SCHEMBL5761090 0.84 MAOA (0.63) MAOACALML3MAOBLMNAPTGS1
SCHEMBL10258335 0.84 MAOA (0.63) MAOACALML3MAOBLMNAPTGS1
SCHEMBL3093375 0.84 MAOA (0.65) MAOACALML3MAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed