Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907228 | 0.88 | PRKCA (0.50) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5442625 | 0.87 | PRKCA (0.45) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5433680 | 0.87 | PRKCA (0.45) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5436038 | 0.86 | PRKCA (0.44) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5436409 | 0.86 | PRKCA (0.44) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5447306 | 0.85 | PRKCA (0.42) | PRKCAMMP12SCN9ACYP2D6 | |
| SCHEMBL5444140 | 0.85 | PRKCA (0.45) | PRKCAMMP12SCN9AKMOMAPT | |
| SCHEMBL5433781 | 0.85 | PRKCA (0.43) | PRKCAMMP12SCN9AMAPTNR1I2 | |
| SCHEMBL5436689 | 0.83 | PRKCA (0.48) | PRKCAMMP12SCN9AKMOLOXL2 | |
| SCHEMBL5438018 | 0.83 | PRKCA (0.46) | PRKCAMMP12SCN9AMAPTFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516158-A | — | — | 2007-06-21 | — | — | JP | claimed |
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | claimed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | claimed |