Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 2/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27669753 | 0.94 | MAPT (0.41) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL28921629 | 0.83 | MAPT (0.40) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL15633632 | 0.78 | MAPT (0.38) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL28610733 | 0.76 | EGLN1 (0.42) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| Citric Acid SCHEMBL28574122 | 0.76 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL15633957 | 0.72 | PHF8 (0.50) | MAPTLMNAALDH1A1CYP3A4TSHR | |
| SCHEMBL19528497 | 0.71 | MAPT (0.64) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL8743295 | 0.71 | MAPT (0.64) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL5011249 | 0.70 | MAPT (0.67) | MAPTLMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL420275 | 0.69 | CYP3A4 (0.75) | MAPTLMNAALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010593-A1 | Pur-polyester flexible foams based on polyetheresterpolyols | BAYER MATERIALSCIENCE AG | 2007-01-11 | — | — | US | disclosed |