Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.40 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454092 | 0.90 | PDE10A (0.42) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL5453179 | 0.90 | PDE10A (0.41) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL4164494 | 0.80 | KDR (0.59) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL4172506 | 0.76 | KDR (0.48) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL5450816 | 0.75 | RIPK1 (0.39) | PDE10AKDRRAF1BRAFSMN1; SMN2 | |
| SCHEMBL5449925 | 0.73 | KDR (0.49) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL14627484 | 0.73 | KDR (0.45) | PDE10AKDRCSNK1A1CSNK1DGSK3B | |
| SCHEMBL5452188 | 0.73 | KDR (0.44) | PDE10AKDRRAF1BRAFCBFB | |
| SCHEMBL5459699 | 0.72 | KDR (0.46) | PDE10AKDRRAF1BRAFCBFB | |
| SCHEMBL5444955 | 0.72 | KDR (0.48) | PDE10AKDRCSNK1A1CSNK1DRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | MERCK PATENT GMBH (DE) | 2007-01-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021456-A1 | Aminobenzimidazole derivatives | TIE1, KDR, FLT1 | PDE10A 4420/4885KDR 2/4885CSNK1A1 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.