Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615244 | 0.85 | HDAC2 (0.46) | HDAC2CNR1AVPR1AHTR1AHTR1D | |
| SCHEMBL5457598 | 0.82 | HDAC2 (0.45) | HDAC2CNR1HTR1AHTR1DHTR1B | |
| SCHEMBL12024747 | 0.74 | KRAS (0.51) | CNR1AVPR1ASMN1; SMN2MEN1MAPT | |
| SCHEMBL615591 | 0.73 | NAMPT (0.43) | CNR1AVPR1AMALT1 | |
| SCHEMBL614385 | 0.69 | AVPR1A (0.55) | CNR1AVPR1ASMN1; SMN2MEN1MAPT | |
| SCHEMBL615451 | 0.69 | SCD (0.44) | CNR1AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL615567 | 0.68 | SMN1; SMN2 (0.53) | CNR1AVPR1ASMN1; SMN2MEN1MAPK1 | |
| SCHEMBL615655 | 0.67 | KRAS (0.55) | CNR1AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL615569 | 0.67 | AVPR1A (0.56) | CNR1AVPR1AMEN1MAPTKMT2A | |
| SCHEMBL27737057 | 0.67 | NAMPT (0.42) | CNR1SMN1; SMN2MALT1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027163-A1 | Indol-3-y-carbonyl-piperidin and piperazin-derivatives | HOFFMANN-LA ROCHE INC. | 2007-02-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027163-A1 | Indol-3-y-carbonyl-piperidin and piperazin-derivatives | AVPR1A, AVPR2, OXTR | HDAC2 1627/4885CNR1 31/4885AVPR1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.