Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 6/20 | 0.36 |
| ▸ | FNTB | P49356 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462994 | 0.92 | DPP4 (0.43) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5450789 | 0.92 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5453675 | 0.89 | DPP4 (0.43) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5449188 | 0.86 | DPP4 (0.46) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5449290 | 0.85 | DPP4 (0.51) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5462030 | 0.85 | KMT2A (0.41) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5443469 | 0.85 | ALDH1A1 (0.44) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL5449955 | 0.83 | DPP4 (0.52) | KMT2AALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL4114038 | 0.83 | DPP4 (0.49) | ALDH1A1MAPTHTTPOLBL3MBTL1 | |
| SCHEMBL5449078 | 0.83 | DPP4 (0.53) | ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | KMT2A 1601/4885ALDH1A1 743/4885LMNA 2641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.