Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41245 | 0.89 | TSHR (0.41) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL1566900 | 0.86 | TSHR (0.39) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL11057751 | 0.86 | TSHR (0.39) | TSHRTHRBALDH1A1LMNA | |
| SCHEMBL15018875 | 0.79 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL1028644 | 0.79 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL1031768 | 0.79 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL1030827 | 0.79 | TSHR (0.46) | TSHRTHRBALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL3930542 | 0.77 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL7984915 | 0.74 | TSHR (0.46) | TSHRTHRBALDH1A1PPARGPPARD | |
| Decane SCHEMBL4518816 | 0.70 | TSHR (0.61) | TSHRTHRBALDH1A1DNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791230-B1 | UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS | DU PONT (US) | 2015-09-16 | — | — | EP | claimed |
| US-9074074-B2 | Polyhydroxy curable fluoroelastomer compositions | THE CHEMOURS COMPANY FC, LLC (US) | 2015-07-07 | — | — | US | claimed |
| EP-2791230-A1 | UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS | E. I. Du Pont de Nemours and Company (US) | 2014-10-22 | — | — | EP | claimed |
| US-20130158200-A1 | POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | claimed |
| WO-2013090535-A1 | UNSATURATED METAL COMPOUND COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | WO | claimed |
| WO-2013090582-A1 | POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | WO | claimed |
| US-20130158154-A1 | COAGENT FOR FREE RADICAL CURING FLUOROELASTOMERS | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | claimed |
| US-20130158155-A1 | COAGENT FOR FREE RADICAL CURING CHLOROROELASTOMERS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | claimed |
| EP-2223946-B1 | Modified natural rubber or modified natural rubber latex and rubber composition | BRIDGESTONE CORP (JP) | 2012-08-22 | — | — | EP | claimed |
| CN-108623894-B | Silane self-crosslinking halogen-free flame retardant material and preparation method and application thereof | 江苏德威新材料股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-3851489-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | BRIDGESTONE CORPORATION (JP) | 2021-07-21 | — | — | EP | disclosed |
| US-10711121-B2 | Rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2020-07-14 | — | — | US | disclosed |
| CN-108473723-B | Rubber composition and tire | 株式会社普利司通 | 2020-06-26 | — | — | CN | disclosed |
| WO-2020054484-A1 | MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT | 株式会社ブリヂストン | 2020-03-19 | — | — | WO | disclosed |
| US-20130158200-A1 | POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | US | disclosed |
| WO-2013090582-A1 | POLYHYDROXY CURABLE FLUOROELASTOMER COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-20 | — | — | WO | disclosed |
| US-20120172491-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2457948-A1 | TIRE | Bridgestone Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |
| US-20070221310-A1 | Pneumatic tire | BRIDGESTONE CORPORATION (JP) | 2007-09-27 | — | — | US | disclosed |
| EP-1818186-A1 | PNEUMATIC TIRE | Bridgestone Corporation (JP) | 2007-08-15 | — | — | EP | disclosed |