Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469361 | 0.92 | DPP4 (0.49) | DPP4ALDH1A1BRAFTHRBMAPT | |
| SCHEMBL5469018 | 0.87 | DPP4 (0.48) | DPP4ALDH1A1BRAFTHRBPIK3CG | |
| SCHEMBL5466456 | 0.87 | ALDH1A1 (0.47) | DPP4ALDH1A1BRAFTHRBMAPT | |
| SCHEMBL5184428 | 0.84 | DPP4 (0.50) | DPP4ALDH1A1BRAFPIK3CGNPSR1 | |
| Hydrochloric Acid SCHEMBL5185532 | 0.84 | DPP4 (0.53) | DPP4ALDH1A1BRAFMAPTPIK3CG | |
| SCHEMBL5463182 | 0.83 | ALDH1A1 (0.57) | DPP4ALDH1A1MAPTNPSR1HSD17B10 | |
| SCHEMBL5464634 | 0.83 | DPP4 (0.57) | DPP4ALDH1A1BRAFPIK3CGNPSR1 | |
| SCHEMBL5458034 | 0.83 | DPP4 (0.69) | DPP4ALDH1A1BRAFPIK3CGCHRM1 | |
| Hydrochloric Acid SCHEMBL5471020 | 0.82 | DPP4 (0.68) | DPP4ALDH1A1BRAFPIK3CGCHRM1 | |
| SCHEMBL5477266 | 0.82 | DPP4 (0.51) | DPP4ALDH1A1BRAFMAPTPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236810-B2 | Substituted 8-aminoalkylthioxanthines, and their use as inhibitors of dipeptidyl peptidase IV | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-08-07 | — | — | US | disclosed |
| US-20070265284-A1 | SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265284-A1 | SUBSTITUTED 8-AMINOALKYLTHIOXANTHINES, AND THEIR USE AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | DPP4, DPP8, DPP7 | DPP4 1/4885ALDH1A1 673/4885BRAF 4380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.