Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 6/20 | 0.38 |
| ▸ | MC4R | P32245 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444782 | 1.00 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| SCHEMBL5444777 | 1.00 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| SCHEMBL5458224 | 1.00 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| SCHEMBL5444788 | 1.00 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5447067 | 0.99 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5449412 | 0.99 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5449420 | 0.99 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5447057 | 0.99 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| Hydrochloric Acid SCHEMBL5447061 | 0.99 | AVPR1A (0.38) | AVPR1AMC4RKDM4EMC5RMC3R | |
| SCHEMBL5444058 | 0.92 | MC4R (0.37) | AVPR1AMC4RKDM4EMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | AVPR1A 12/4885MC4R 1/4885KDM4E 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.