Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5740583 | 0.92 | DPP4 (0.42) | DPP4DPP9DPP8NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5446360 | 0.85 | DPP4 (0.56) | DPP4DPP9DPP8NPC1RAB9A | |
| SCHEMBL5445193 | 0.81 | DPP4 (0.48) | DPP4DPP9DPP8TP53POLB | |
| SCHEMBL5457120 | 0.81 | DPP4 (0.52) | DPP4DPP9DPP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL5740578 | 0.80 | DPP4 (0.40) | DPP4DPP9DPP8NPC1RAB9A | |
| SCHEMBL4119064 | 0.78 | DPP4 (0.60) | DPP4DPP9DPP8 | |
| SCHEMBL5442503 | 0.78 | DPP4 (0.49) | DPP4DPP9DPP8NPC1RAB9A | |
| SCHEMBL5463024 | 0.78 | DPP4 (0.49) | DPP4DPP9DPP8NPC1RAB9A | |
| SCHEMBL5443496 | 0.78 | DPP4 (0.48) | DPP4DPP9DPP8SMN1; SMN2L3MBTL1 | |
| SCHEMBL5442960 | 0.76 | DPP4 (0.66) | DPP4DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037807-A1 | Pyridine compounds as inhibitors of dipeptidyl peptidase IV | DPP4, DPP3, PEPD | DPP4 1/4885DPP9 5/4885DPP8 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.