Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14992884 | 1.00 | TSHR (0.40) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL28243 | 0.88 | TSHR (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL5865632 | 0.80 | SLC22A6 (0.50) | ALDH1A1HSD17B10L3MBTL1SLC22A6KDM4E | |
| SCHEMBL854003 | 0.79 | — | — | |
| SCHEMBL12787282 | 0.79 | MGAM (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL2413537 | 0.79 | SLC22A6 (0.62) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL7734688 | 0.79 | — | — | |
| SCHEMBL15976653 | 0.79 | MGAM (0.50) | TSHRALDH1A1HSD17B10MGAMGAA | |
| SCHEMBL1554944 | 0.79 | — | — | |
| SCHEMBL13908456 | 0.79 | MGAM (0.50) | TSHRALDH1A1HSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066846-B | The method that chiral statin side chain intermediate is prepared using candida antarctica lipase B | 迈兰实验室有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-104066846-A | Process for producing chiral statin side chain intermediates employing candida|antarctica lipase B | MYLAN LAB LTD | 2014-09-24 | — | — | CN | disclosed |
| US-20070043010-A1 | Quinazoline derivatives | ASTRAZENECA UK LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043010-A1 | Quinazoline derivatives | ERBB2, ABL1, EGFR | TSHR 1244/4885ALDH1A1 2808/4885HSD17B10 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.