Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 7/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | LTK | P29376 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14900758 | 0.92 | TOP1 (0.46) | TOP1PIK3CATOP2ACLK2DYRK1A | |
| SCHEMBL5456759 | 0.92 | TOP1 (0.50) | TOP1PIK3CACYP19A1TOP2ACLK2 | |
| SCHEMBL1226790 | 0.92 | TOP1 (0.53) | TOP1PIK3CATOP2ACLK2DYRK1A | |
| SCHEMBL22709781 | 0.88 | CYP19A1 (0.51) | TOP1PIK3CACYP19A1CLK2DYRK1A | |
| SCHEMBL22709514 | 0.88 | CYP19A1 (0.51) | TOP1PIK3CACYP19A1CLK2DYRK1A | |
| SCHEMBL22709483 | 0.88 | CYP19A1 (0.51) | TOP1PIK3CACYP19A1CLK2DYRK1A | |
| SCHEMBL22710022 | 0.88 | CYP19A1 (0.51) | TOP1PIK3CACYP19A1CLK2DYRK1A | |
| SCHEMBL14581500 | 0.87 | PIK3CA (0.46) | TOP1PIK3CACYP19A1TOP2ACLK2 | |
| SCHEMBL3355970 | 0.87 | KDM4E (0.52) | TOP1PIK3CATOP2AMAP4K4PRKACA | |
| SCHEMBL5456861 | 0.86 | TOP1 (0.43) | TOP1PIK3CATOP2ACLK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037983-A1 | Phenanthroline derivative compound | POP1, PABPC1, NAP1L1 | TOP1 113/4885PIK3CA 4850/4885CYP19A1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.