Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815685 | 0.95 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL30542209 | 0.93 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL30542201 | 0.87 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL6441357 | 0.86 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL6811241 | 0.84 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL30542208 | 0.82 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL28401848 | 0.81 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL6811060 | 0.81 | MAPT (0.63) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL6813918 | 0.81 | HTT (0.61) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT | |
| SCHEMBL24169278 | 0.80 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |