Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114512 | 0.85 | TLR7 (0.56) | TLR7TLR8CNR1CNR2 | |
| SCHEMBL5454598 | 0.84 | BRD4 (0.41) | TLR7CNR1CNR2 | |
| SCHEMBL4531403 | 0.83 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL3867981 | 0.79 | TLR7 (0.69) | TLR7TLR8 | |
| SCHEMBL3862331 | 0.74 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL3861967 | 0.74 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL4242646 | 0.74 | TLR7 (0.61) | TLR7TLR8 | |
| SCHEMBL3870393 | 0.72 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL4523977 | 0.72 | TLR7 (0.55) | TLR7TLR8CNR2 | |
| SCHEMBL4519468 | 0.72 | TLR7 (0.56) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | IL2, IL4, IRF3 | TLR7 55/4885TLR8 93/4885CNR1 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.