Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209010 | 0.79 | KDM4E (0.48) | KDM4EMAPTNPC1ALDH1A1GLA | |
| SCHEMBL6209007 | 0.79 | KDM4E (0.48) | KDM4EMAPTNPC1ALDH1A1GLA | |
| SCHEMBL28582151 | 0.70 | KMT2A (0.36) | ADRA2AADRA2BADRA2CMAPTALDH1A1 | |
| Bromide SCHEMBL28409162 | 0.69 | KMT2A (0.35) | ADRA2AADRA2BADRA2CMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL28475833 | 0.69 | TLR8 (0.36) | ADRA2AADRA2BADRA2CMAPTALDH1A1 | |
| SCHEMBL23367993 | 0.69 | KMT2A (0.35) | ADRA2AADRA2BADRA2CMAPTALDH1A1 | |
| SCHEMBL11597308 | 0.67 | GRM4 (0.42) | KDM4EMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL11597305 | 0.67 | GRM4 (0.42) | KDM4EMAPTNPC1ALDH1A1RAB9A | |
| SCHEMBL6886638 | 0.65 | — | — | |
| SCHEMBL1206354 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219246-A1 | Dihydrobenzothiophenes | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219246-A1 | Dihydrobenzothiophenes | CCNT1, CCNT2, TPT1 | TOP2A 177/4885TOP2B 129/4885ADRA2A 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.