Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28582151 | 0.98 | KMT2A (0.36) | KMT2AALDH1A1POLBTLR8MAPT | |
| Hydrochloric Acid SCHEMBL28475833 | 0.96 | TLR8 (0.36) | KMT2AALDH1A1POLBTLR8MAPT | |
| SCHEMBL23367993 | 0.81 | KMT2A (0.35) | KMT2AALDH1A1POLBTLR8MAPT | |
| Bromide SCHEMBL30948884 | 0.78 | MAPT (0.37) | KMT2AALDH1A1POLBTLR8MAPT | |
| SCHEMBL8763026 | 0.78 | FPR2 (0.33) | KMT2AALDH1A1POLBTLR8 | |
| SCHEMBL1206354 | 0.76 | — | — | |
| SCHEMBL6886638 | 0.76 | — | — | |
| SCHEMBL8763159 | 0.75 | KDM4E (0.38) | KMT2AALDH1A1POLBMAPT | |
| SCHEMBL6209007 | 0.75 | KDM4E (0.48) | KMT2AALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL29006295 | 0.75 | ALDH1A1 (0.42) | KMT2AALDH1A1POLBTLR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285951-B | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2022-10-18 | — | — | CN | claimed |
| CN-111285951-A | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2020-06-16 | — | — | CN | claimed |
| CN-118702875-A | Gelatin-based hydrogel and preparation method and application thereof | 陕西科技大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-111285951-B | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2022-10-18 | — | — | CN | disclosed |
| CN-111811702-A | High-recovery conductive film pressure sensor and preparation method thereof | 无锡康森斯克电子科技有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111285951-A | Lipase/polyion liquid-styrene microsphere/hydrogel catalytic material and preparation method and application thereof | 大连工业大学 | 2020-06-16 | — | — | CN | disclosed |