SCHEMBL5459734

SCHEMBL5459734

C=CC(=O)Oc1cccc(Br)c1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.44
THRB P10828 4/20 0.43
THRA P10827 1/20 0.43
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALDH1A1 P00352 1/20 0.34
LIG1 P18858 1/20 0.34
NCEH1 Q6PIU2 3/20 0.33
TGM2 P21980 1/20 0.33
LY96 Q9Y6Y9 1/20 0.33
USP2 O75604 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GRM4 Q14833 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1215245 0.85 THRB (0.49) TYMSTHRBTHRAMAPTKDM4E
SCHEMBL9171010 0.85 MAPT (0.50) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL9171000 0.85 MAPT (0.50) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL30596851 0.85 THRB (0.49) TYMSTHRBTHRAMAPTKDM4E
SCHEMBL28108083 0.85 MAPT (0.50) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL9857933 0.85 TYMS (0.38) TYMSTHRBTHRANCEH1
SCHEMBL331642 0.84 TYMS (0.42) TYMSTHRBTHRAMAPTHPGD
SCHEMBL30596831 0.84 TYMS (0.42) TYMSTHRBTHRAMAPTHPGD
SCHEMBL23000268 0.83 THRB (0.41) TYMSTHRBTHRAMAPTKDM4E
SCHEMBL28430016 0.83 MRGPRX4 (0.43) TYMSTHRBTHRAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0320954-A2 Transparent resin and transparent resin products NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-06-21 EP claimed
CN-105566021-A Preparation method of alpha, beta-unsaturated carboxylic acid compounds UNIV SCIENCE & TECH CHINA 2016-05-11 CN disclosed
US-20130114119-A1 HOLOGRAM AND DEVICE COMPRISING A HOLOGRAM SONY DADC AUSTRIA AG (AT) 2013-05-09 US disclosed
EP-2590031-A1 Hologram and device comprising a hologram Sony DADC Austria AG (AT) 2013-05-08 EP disclosed
US-20130003153-A1 HOLOGRAM AND METHOD OF FORMING A HOLOGRAM SONY DADC AUSTRIA AG (AT) 2013-01-03 US disclosed
EP-2541343-A1 Hologram and method of forming a hologram Sony DADC Austria AG (AT) 2013-01-02 EP disclosed
US-20070184353-A1 Volume hologram recording material and volume hologram recording medium TOAGOSEI CO., LTD. (JP) 2007-08-09 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
EP-1729184-A1 VOLUME HOLOGRAM RECORDING MATERIAL AND VOLUME HOLOGRAM RECORDING MEDIUM TOAGOSEI CO., LTD. (JP) 2006-12-06 EP disclosed
US-7140741-B2 Color shifting retroreflector and method of making same 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-11-28 US disclosed
EP-0320954-A2 Transparent resin and transparent resin products NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-06-21 EP disclosed
US-4812032-A DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE TORAY INDUSTRIES, INC. (JP) 1989-03-14 US disclosed
EP-0170913-B1 ETHYLENE COPOLYMER AND PROCESS FOR THE PRODUCTION THEREOF MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-03-08 EP disclosed
US-4721377-A COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE TORAY INDUSTRIES, INC. (JP) 1988-01-26 US disclosed
EP-0134861-B1 RESIN MATERIAL FOR PLASTIC LENS AND LENS COMPOSED THEREOF TORAY INDUSTRIES, INC. (JP) 1987-12-09 EP disclosed
EP-0176874-A2 A highly-refractive plastic lens TORAY INDUSTRIES, INC. (JP) 1986-04-09 EP disclosed
EP-0170913-A2 Ethylene copolymer and process for the production thereof MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-02-12 EP disclosed
EP-0134861-A1 Resin material for plastic lens and lens composed thereof TORAY INDUSTRIES, INC. (JP) 1985-03-27 EP disclosed
US-4487904-A Urethanized acrylic resin material for plastic lens and lens composed thereof TORAY INDUSTRIES, INC. (JP) 1984-12-11 US disclosed
US-4369298-A Novel cured resin, process for production thereof, and lens composed of said resin from bis(alkyleneoxyphenyl)-diacrylate, bis(alkyleneoxyphenyl)diallyl ether, bis(alkyleneoxyphenyl)diallyl carbonate monomers TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1983-01-18 US disclosed