SCHEMBL5459783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5467348	0.86	FLT3 (0.47)	FLT3MAPK10GFERMEN1KMT2A
	SCHEMBL14361160	0.83	FLT3 (0.44)	FLT3MAPK10GFERMEN1KMT2A
	SCHEMBL5460557	0.83	FLT3 (0.51)	FLT3MAPK10MEN1KMT2ANPC1
	SCHEMBL5448452	0.82	NAMPT (0.49)	FLT3MAPK10MEN1KMT2ANPC1
	SCHEMBL5450627	0.80	AURKA (0.50)	FLT3GFERMEN1KMT2ANPC1
	SCHEMBL5466117	0.80	FLT3 (0.48)	FLT3MAPK10GFERKMT2ANPC1
	SCHEMBL5450964	0.80	FLT3 (0.48)	FLT3MAPK10GFERAURKAAURKB
	SCHEMBL5460352	0.79	AURKA (0.43)	FLT3MAPK10MEN1KMT2ANPC1
	SCHEMBL5453459	0.79	AURKA (0.43)	FLT3MAPK10MEN1KMT2ANPC1
	SCHEMBL17611488	0.78	FLT3 (0.46)	FLT3MAPK10GFERMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.