Biphenyl

Biphenyl

SCHEMBL5459788

CC(Cl)(Cl)Cl.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.60

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.60
CYP1A2 P05177 2/20 0.50
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
SLC22A3 O75751 1/20 0.46
SLC6A4 P31645 1/20 0.46
TSHR P16473 2/20 0.45
TAAR1 Q96RJ0 2/20 0.43
MAOA P21397 1/20 0.43
KIF11 P52732 1/20 0.43
MAPK1 P28482 2/20 0.43
CYP3A4 P08684 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NOTUM Q6P988 1/20 0.43
MMP3 P08254 1/20 0.43
BCL2L1 Q07817 1/20 0.43
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL22288245 0.90 ALDH1A1 (0.56) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL2598157 0.89 ALDH1A1 (0.75) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL28147171 0.88 ALDH1A1 (0.53) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27550995 0.86 ALDH1A1 (0.69) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27335451 0.86 ALDH1A1 (0.69) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27709311 0.86 ALDH1A1 (0.69) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Biphenyl SCHEMBL27745920 0.86 ALDH1A1 (0.69) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
SCHEMBL2468018 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
SCHEMBL8463 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3
Benzene SCHEMBL6754211 0.82 ALDH1A1 (0.90) ALDH1A1CYP1A2SLC22A2SLC22A1SLC22A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292409-A Electrolytically generating superoxide ion under protective layer of ion exchange material CAPE COD RESEARCH, INC. (US) 1994-03-08 US claimed
US-3932527-A CONDENSATION OF CHLORAL WITH A BENZENE, ACID CATALYST UNIVERSITY OF ILLINOIS FOUNDATION (US) 1976-01-13 US claimed
US-20070009563-A1 PROCESS FOR COATING FIBER OR FABRIC WITH INSECTICIDE USING A TEMPERATURE OF 150°C-190°C FOR DRYING NETTO GROUP CO., LTD (TH) 2007-01-11 US disclosed
CN-1026689-C Process for dehydrochlorination of 1, 1-bis (R-phenyl) -2, 2, 2-trichloroethane ATOCHEM ELF SA (FR) 1994-11-23 CN disclosed
US-5292409-A Electrolytically generating superoxide ion under protective layer of ion exchange material CAPE COD RESEARCH, INC. (US) 1994-03-08 US disclosed
CN-1068101-A 1, two (the R-phenyl)-2,2 of 1-, the method for 2-trichloroethane dehydrochlorination FLF ATOCHEM S A (FR) 1993-01-20 CN disclosed
EP-0057153-B1 BIOCIDAL SUBSTANCES CONTAINING EMULSIFIABLE CONCENTRATES, AQUEOUS EMULSIONS OBTAINED THEREFROM AND UTILIZATION THEREOF FOR TREATING WOOD XYLOCHIMIE (FR) 1986-04-30 EP disclosed
EP-0055476-B1 DEGRADATION OF HALOGENATED CARBON COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1986-01-02 EP disclosed
US-4410402-A SUPEROXIDE, APROTIC SOLVENT REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-10-18 US disclosed
EP-0057153-A2 Biocidal substances containing emulsifiable concentrates, aqueous emulsions obtained therefrom and utilization thereof for treating wood XYLOCHIMIE (FR) 1982-08-04 EP disclosed
EP-0055476-A1 Degradation of halogenated carbon compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1982-07-07 EP disclosed
US-4192957-A DEHYDROCHLORINATION OF 1,1,1-TRICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHANE TO 1,1-DICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHYLENE WITH LIQUID AMMONIA AND ALKYL AMINE HYDROHALIDE PROMOTER GENERAL ELECTRIC COMPANY (US) 1980-03-11 US disclosed
US-4192956-A DEHYDROCHLORINATION OF 1,1,1-TRICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHANE TO 1,1-DICHLORO-2,2-BIS(4-HYDROXYPHENYL)ETHYLENE WITH LIQUID AMMONIA AND INORGANIC HALIDE PROMOTER GENERAL ELECTRIC COMPANY (US) 1980-03-11 US disclosed
US-4178466-A Process for preparing phenyl trichloro-ethanes GENERAL ELECTRIC COMPANY (US) 1979-12-11 US disclosed
US-4105857-A CONDENSING PHENOL AND CHLORAL IN A SULFURIC ACID- METHYLENE CHLORIDE SOLVENT SYSTEM GENERAL ELECTRIC COMPANY (US) 1978-08-08 US disclosed