Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.53 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5447615 | 0.87 | FLT3 (0.56) | ANO1CFTRCHRNA7MAPTPOLB | |
| SCHEMBL5450945 | 0.85 | CFTR (0.54) | ANO1CFTRKCNH2CNR2CNR1 | |
| SCHEMBL5447523 | 0.84 | CFTR (0.56) | ANO1CFTRKCNH2CNR2CNR1 | |
| SCHEMBL5450655 | 0.84 | CFTR (0.54) | ANO1CFTRKCNH2CNR2CNR1 | |
| SCHEMBL5451368 | 0.84 | CHRNA7 (0.47) | CFTRCHRNA7MAPTTP53GAA | |
| SCHEMBL5460654 | 0.83 | ANO1 (0.64) | ANO1CFTRKCNH2CNR2CNR1 | |
| SCHEMBL5460167 | 0.83 | KDR (0.60) | ANO1CFTRMAPTKCNH2CNR2 | |
| SCHEMBL5453563 | 0.83 | CFTR (0.52) | ANO1CFTRMAPTKCNH2CNR2 | |
| SCHEMBL5454317 | 0.81 | MEN1 (0.63) | ANO1CFTRMAPTKCNH2CNR2 | |
| SCHEMBL5457877 | 0.80 | CFTR (0.57) | ANO1CFTRMAPTKCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | claimed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | ANO1 3245/4885CFTR 2030/4885CHRNA7 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.