Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPY1R | P25929 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081588 | 0.89 | ALDH1A1 (0.65) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4069789 | 0.88 | ALDH1A1 (0.53) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4073221 | 0.84 | POLB (0.69) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL5454251 | 0.83 | MAPT (0.54) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4081580 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4074569 | 0.81 | GUSB (0.60) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4072964 | 0.76 | GUSB (0.59) | ALDH1A1NPSR1GUSBKDM4EMEN1 | |
| SCHEMBL4077438 | 0.75 | KDM4E (0.54) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4073864 | 0.74 | KDM4E (0.55) | ALDH1A1NPSR1SMN1; SMN2GUSBKDM4E | |
| SCHEMBL4077914 | 0.74 | ALDH1A1 (0.55) | ALDH1A1NPSR1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | claimed |
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | ALDH1A1 1055/4885NPSR1 4425/4885SMN1; SMN2 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.