SCHEMBL546124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11888601	0.95	TLR9 (0.37)	EPHA2ERBB2EPHB4CHEK2EHMT2
	SCHEMBL12027365	0.90	MAPK1 (0.39)	CXCR3ALDH1A1MAPK1KDM4EHPGD
	SCHEMBL14163870	0.86	CD274 (0.40)	CXCR3ALDH1A1MAPK1KDM4EHPGD
	SCHEMBL546463	0.84	ITK (0.38)	EPHA2ERBB2EPHB4CXCR3ALDH1A1
	SCHEMBL1645959	0.80	ACHE (0.41)	CHEK2CXCR3ALDH1A1MAPK1KDM4E
	SCHEMBL10240147	0.80	SSTR4 (0.41)	ALDH1A1MAPK1KDM4EHPGDSMN1; SMN2
	Trifluoroacetic Acid SCHEMBL546625	0.77	SSTR4 (0.39)	ALDH1A1MAPK1KDM4EHPGDSMN1; SMN2
	SCHEMBL12252951	0.76	NR1H2 (0.43)	CHEK2KMT2A
	SCHEMBL1645725	0.75	KDM4E (0.45)	ALDH1A1KDM4EHSD17B10
	SCHEMBL8302949	0.75	KDM4E (0.45)	ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.