Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL545341 | 0.88 | RAF1 (0.73) | RAF1BRAF | |
| SCHEMBL545889 | 0.88 | BRAF (0.63) | RAF1BRAF | |
| SCHEMBL545402 | 0.88 | RAF1 (0.61) | RAF1BRAF | |
| SCHEMBL10200944 | 0.87 | RAF1 (0.60) | RAF1BRAF | |
| SCHEMBL546138 | 0.86 | BRAF (0.62) | RAF1BRAF | |
| SCHEMBL545326 | 0.86 | BRAF (0.83) | RAF1BRAF | |
| SCHEMBL546037 | 0.86 | BRAF (0.69) | RAF1BRAF | |
| SCHEMBL546169 | 0.86 | BRAF (0.68) | RAF1BRAF | |
| SCHEMBL546087 | 0.85 | BRAF (0.68) | RAF1BRAF | |
| SCHEMBL545560 | 0.85 | BRAF (0.68) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110687-B2 | Bicyclic compounds with kinase inhibitory activity | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-07 | — | — | US | disclosed |