Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | F12 | P00748 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL2382227 | 0.92 | CA12 (0.44) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL1997779 | 0.90 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL5491910 | 0.87 | CA12 (0.61) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL8354282 | 0.87 | CA12 (0.69) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL447771 | 0.87 | CA12 (0.69) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL3402090 | 0.86 | TDP1 (0.52) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL27501631 | 0.85 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL1921716 | 0.85 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL891772 | 0.81 | CA12 (0.52) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL20797973 | 0.81 | CA12 (0.52) | CA12CA1CA2GLACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115651968-A | Whole transcriptome RNA standard substance of human B lymphocyte cell line of family of homozygote twins, preparation method and application | 中国计量科学研究院 | 2023-01-31 | — | — | CN | claimed |
| CN-1710102-A | PCR detecting method of tumour associated gene mutation and reagent system | SHANGHAI LUNG DIVISION HOSPITA (CN) | 2005-12-21 | — | — | CN | claimed |
| CN-118359714-A | Anti-MCM 2 mouse monoclonal antibody, preparation method thereof and application of immunohistochemical reagent | 浙江莱阅病理诊断科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-112313335-B | Renin (AGT) iRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118256485-A | Kit for rapidly extracting nucleic acid and application | 上海市肺科医院 | 2024-06-28 | — | — | CN | disclosed |
| CN-118240941-A | Method and kit for quantitatively detecting acute leukemia MLL-AF4 fusion gene by ddPCR | 中南大学湘雅医院 | 2024-06-25 | — | — | CN | disclosed |
| CN-118240938-A | Method and kit for quantitatively detecting 2 acute lymphoblastic leukemia fusion genes by ddPCR | 中南大学湘雅医院 | 2024-06-25 | — | — | CN | disclosed |
| CN-118251489-A | Regulation of gene transcription using antisense oligonucleotides targeted to regulatory RNAs | 4阵营疗法公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118222701-A | Development and application of EGFP (enhanced green fluorescent protein) reporting system for identifying N4BP1 endoribonuclease activity | 南通大学 | 2024-06-21 | — | — | CN | disclosed |
| EP-4386088-A1 | METHOD FOR THE ACCURATE QUANTIFICATION OF NON-CODING RNAS IN MINUTE QUANTITIES | Johannes Gutenberg-Universität Mainz (DE) | 2024-06-19 | — | — | EP | disclosed |
| CN-118159654-A | Inhibin subunit beta E (INHBE) modulator compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2024-06-07 | — | — | CN | disclosed |
| US-5616468-A | HYBRIDOMA-PRODUCED ANTIBODY THAT BINDS TO POLYPEPTIDE AND GLYCOPROTEIN CD44V6 BUT NOT TO STANDARD LYMPHOCYTE FORM; DIAGNOSIS OF MALIGNANT TRANSFORMATION OF CELLS, INFLAMMATORY DISEASES | OY FARON PHARMACEUTICALS LTD. (FI) | 1997-04-01 | — | — | US | disclosed |
| WO-1997011177-A1 | NEUTRALIZING MONOCLONAL ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS | INTRACEL CORPORATION (US) | 1997-03-27 | — | — | WO | disclosed |
| WO-1997010846-A1 | NEUTRALIZING MONOCLONAL ANTIBODIES TO RESPIRATORY SYNCYTIAL VIRUS | INTRACEL CORPORATION (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0743982-A1 | IMMORTALIZED HUMAN FETAL OSTEOBLASTIC CELLS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1996-11-27 | — | — | EP | disclosed |
| WO-1996023067-A1 | HUMAN INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN | F.HOFFMANN-LA ROCHE AG (CH) | 1996-08-01 | — | — | WO | disclosed |
| WO-1996015272-A9 | NEURAL THREAD PROTEIN GENE EXPRESSION AND DETECTION OF ALZHEIMER'S DISEASE | — | 1996-07-25 | — | — | WO | disclosed |
| WO-1996015272-A1 | NEURAL THREAD PROTEIN GENE EXPRESSION AND DETECTION OF ALZHEIMER'S DISEASE | THE GENERAL HOSPITAL CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995002687-A1 | IMMORTALIZED HUMAN FETAL OSTEOBLASTIC CELLS | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1995-01-26 | — | — | WO | disclosed |
| CN-1083389-A | New antitumor cell activin | RES DEV FOUNDATION (US) | 1994-03-09 | — | — | CN | disclosed |