Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA3 | P07451 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | F12 | P00748 | 1/20 | 0.52 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL8354282 | 1.00 | CA12 (0.69) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27501631 | 0.97 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL1921716 | 0.97 | CA12 (0.65) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL28497921 | 0.92 | CA12 (0.58) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27478117 | 0.89 | CA12 (0.55) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL887189 | 0.89 | CA12 (0.55) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL546282 | 0.87 | CA12 (0.52) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL6009739 | 0.87 | CA12 (0.52) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL20797973 | 0.87 | CA12 (0.52) | CA12CA2CA9CA14CA1 | |
| Phenol SCHEMBL27435926 | 0.87 | TDP1 (0.52) | CA12CA2CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102190810-B | Method for preparing brominated-polyphenylene-ether-guanidination-based homogeneous anion exchange membrane | USTC UNIV SCIENCE TECH CN | 2012-10-03 | — | — | CN | claimed |
| CN-102190810-A | Method for preparing brominated-polyphenylene-ether-guanidination-based homogeneous anion exchange membrane | USTC UNIV SCIENCE TECH CN | 2011-09-21 | — | — | CN | claimed |
| JP-2004526678-A | — | — | 2004-09-02 | — | — | JP | claimed |
| JP-2004521094-A | — | — | 2004-07-15 | — | — | JP | claimed |
| US-6521777-B2 | Process for the production of diaryl carbonates | GENERAL ELECTRIC COMPANY | 2003-02-18 | — | — | US | claimed |
| US-20020111507-A1 | Process for the production of diaryl carbonates | OFORI JOHN YAW (US) | 2002-08-15 | — | — | US | claimed |
| US-6420589-B1 | Process for the production of diaryl carbonates | GENERAL ELECTRIC COMPANY | 2002-07-16 | — | — | US | claimed |
| US-20020077496-A1 | Process for the production of diaryl carbonates | GENERAL ELECTRIC COMPANY | 2002-06-20 | — | — | US | claimed |
| US-20020077495-A1 | Process for the production of diaryl carbonates | GENERAL ELECTRIC COMPANY | 2002-06-20 | — | — | US | claimed |
| US-20020077497-A1 | PROCESS FOR THE PRODUCTION OF DIARYL CARBONATES | GENERAL ELECTRIC COMPANY | 2002-06-20 | — | — | US | claimed |
| WO-2002048088-A2 | PROCESS FOR THE PRODUCTION OF DIARYL CARBONATES | GENERAL ELECTRIC COMPANY (US) | 2002-06-20 | — | — | WO | claimed |
| WO-2002048087-A2 | PROCESS FOR THE PRODUCTION OF DIARYL CARBONATES | GENERAL ELECTRIC COMPANY A CORPORATION OF THE STATE OF NEW YORK (US) | 2002-06-20 | — | — | WO | claimed |
| CN-1033080-A | Thread supply monitoring device in thread supply equipment for textile machinery | MEMMINGER GUSTAV (DE) | 1989-05-24 | — | — | CN | claimed |
| US-4452692-A | Process for the hydrogenation of heavy oils | KNEISSL HANNES | 1984-06-05 | — | — | US | claimed |
| US-4388170-A | GUANIDINIUM COMPOUND | SCHMID KLAUS (DE) | 1983-06-14 | — | — | US | claimed |
| EP-0030020-B1 | PROCESS FOR THE OBTENTION OF LOW MOLECULAR WEIGHT HYDROCARBONS FROM HIGH MOLECULAR WEIGHT HYDROCARBONS OR FROM COAL | WASAGCHEMIE HOLDING ZUG AG (CH) | 1982-05-19 | — | — | EP | claimed |
| EP-0030020-A1 | Process for the obtention of low molecular weight hydrocarbons from high molecular weight hydrocarbons or from coal | WASAGCHEMIE HOLDING ZUG AG (CH) | 1981-06-10 | — | — | EP | claimed |
| US-4025466-A | CATALYTIC MIXTURE OF FUSED HETEROCYCLIC COMPOUND CONTAINING AMIDINE GROUP AND SALT OF CARBOXYLIC ACID | S.A. PRB (BE) | 1977-05-24 | — | — | US | claimed |
| CN-117925631-A | Nucleotide sequence for regulating rice grain shape and grain weight and application thereof | 江西农业大学 | 2024-04-26 | — | — | CN | disclosed |
| US-4025466-A | CATALYTIC MIXTURE OF FUSED HETEROCYCLIC COMPOUND CONTAINING AMIDINE GROUP AND SALT OF CARBOXYLIC ACID | S.A. PRB (BE) | 1977-05-24 | — | — | US | disclosed |