Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | TOP1 | P11387 | 4/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458967 | 0.91 | DHODH (0.51) | DHODHACACAMETAP2MAPK1ADORA3 | |
| SCHEMBL5456759 | 0.88 | TOP1 (0.50) | TOP1ACACATOP2AMAPK1ADORA3 | |
| SCHEMBL1226790 | 0.88 | TOP1 (0.53) | TOP1ACACATOP2AMAPK1ADORA3 | |
| SCHEMBL5467861 | 0.85 | KDM4E (0.50) | TOP1ACACATOP2AADORA2AADORA1 | |
| SCHEMBL19768563 | 0.83 | TOP1 (0.49) | DHODHTOP1TGFBR1ACACATOP2A | |
| SCHEMBL29371113 | 0.83 | CYP1A1 (0.47) | TOP1ACACATOP2AADORA2AADORA1 | |
| SCHEMBL184981 | 0.83 | CYP1A1 (0.47) | TOP1ACACATOP2AADORA2AADORA1 | |
| SCHEMBL22139710 | 0.83 | TOP1 (0.46) | TOP1ACACATOP2AMAPK1KDM4E | |
| SCHEMBL16696500 | 0.83 | TOP1 (0.49) | DHODHTOP1TGFBR1ACACATOP2A | |
| SCHEMBL3355970 | 0.82 | KDM4E (0.52) | TOP1TOP2AMAPK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
| US-20070037983-A1 | Phenanthroline derivative compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037983-A1 | Phenanthroline derivative compound | POP1, PABPC1, NAP1L1 | DHODH 1869/4885TOP1 113/4885TGFBR1 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.