SCHEMBL5464396

SCHEMBL5464396

S=C(NCc1cc(Cl)cc(Cl)c1)Nc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
HPGD P15428 2/20 0.74
ALOX12 P18054 2/20 0.74
MAOB P27338 4/20 0.70
MAOA P21397 2/20 0.70
MAPT P10636 4/20 0.69
NPSR1 Q6W5P4 1/20 0.69
LMNA P02545 2/20 0.68
PLA2G1B P04054 1/20 0.68
ATG4B Q9Y4P1 1/20 0.68
CYP19A1 P11511 1/20 0.63
ALDH1A1 P00352 2/20 0.62
PPARG P37231 1/20 0.62
NCOA3 Q9Y6Q9 1/20 0.62
CA9 Q16790 1/20 0.60
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5450570 0.88 MAOB (0.83) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL9529477 0.87 MAOB (0.78) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL28542586 0.85 MEN1 (1.00) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL6814362 0.84 CYP19A1 (0.60) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL8615717 0.84 MAOB (0.78) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL1520659 0.83 MAOB (1.00) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL30388749 0.81 MAOB (0.83) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL9123997 0.81 MAOB (1.00) MEN1KMT2AHPGDALOX12MAOB
SCHEMBL6819391 0.80 KMT2A (0.57) MEN1KMT2AHPGDALOX12MAPT
SCHEMBL6814359 0.80 KDM4E (0.57) MEN1KMT2AHPGDALOX12MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed