SCHEMBL9529477

SCHEMBL9529477

S=C(NCc1ccccc1)Nc1cc(Cl)cc(Cl)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.78
HPGD P15428 3/20 0.78
LMNA P02545 2/20 0.78
PLA2G1B P04054 1/20 0.78
ATG4B Q9Y4P1 1/20 0.78
MAPT P10636 5/20 0.74
NPSR1 Q6W5P4 2/20 0.74
MAPK1 P28482 1/20 0.70
MAOA P21397 2/20 0.70
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
ALOX12 P18054 3/20 0.69
CYP19A1 P11511 1/20 0.63
MYC P01106 1/20 0.62
MAX P61244 1/20 0.62
RAB9A P51151 2/20 0.61
NPC1 O15118 1/20 0.61
ALDH1A1 P00352 3/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
POLB P06746 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615717 0.97 MAOB (0.78) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL9123997 0.88 MAOB (1.00) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL5464396 0.87 MEN1 (0.74) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL9530086 0.84 MAPT (0.76) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL6816138 0.84 MAPT (0.59) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL4355796 0.84 MAPT (0.66) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL26485880 0.84 LMNA (0.76) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL26485863 0.83 MAPT (0.64) MAOBHPGDLMNAPLA2G1BATG4B
SCHEMBL26485849 0.83 MAPT (1.00) HPGDLMNAMAPTMAPK1MEN1
SCHEMBL8612547 0.83 MAOB (0.92) MAOBHPGDLMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134821-A1 MYC-MAX INHIBITOR COMPOUND THERAPEUTICS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-05-04 US disclosed
US-20230134821-A1 MYC-MAX INHIBITOR COMPOUND THERAPEUTICS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2023-05-04 US disclosed
EP-0299533-B1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1993-04-07 EP disclosed
WO-1989000563-A1 HIGH POTENCY SWEETENING AGENTS THE NUTRASWEET COMPANY (US) 1989-01-26 WO disclosed
EP-0299533-A2 High potency sweetening agents THE NUTRASWEET COMPANY (a Delaware corporation) (US) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134821-A1 MYC-MAX INHIBITOR COMPOUND THERAPEUTICS FOR CANCER TREATMENT, METHODS AND USES ASSOCIATED THEREWITH MYC, MYCBP, MAX MAOB 2387/4885HPGD 3384/4885LMNA 411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.