Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469673 | 0.95 | EGFR (0.57) | EGFR | |
| SCHEMBL5469688 | 0.93 | EGFR (0.57) | EGFR | |
| SCHEMBL5463621 | 0.93 | EGFR (0.56) | EGFR | |
| SCHEMBL5461135 | 0.89 | EGFR (0.54) | EGFR | |
| SCHEMBL5465190 | 0.88 | EGFR (0.60) | EGFR | |
| SCHEMBL5469445 | 0.88 | MEN1 (0.49) | EGFR | |
| SCHEMBL5471305 | 0.87 | EGFR (0.57) | EGFR | |
| SCHEMBL5477525 | 0.87 | EGFR (0.65) | EGFR | |
| SCHEMBL5472870 | 0.85 | EGFR (0.56) | EGFR | |
| SCHEMBL5471148 | 0.85 | EGFR (0.56) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244133-A1 | Thienopyrimidines and Thiazolopyrimidines for Use in Medicine | ASTRAZENECA AB (SE) | 2007-10-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244133-A1 | Thienopyrimidines and Thiazolopyrimidines for Use in Medicine | CXCR4, CXCR1, CXCR3 | EGFR 4385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.