Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.68 |
| ▸ | CES1 | P23141 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.67 |
| ▸ | PLAU | P00749 | 2/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | PLG | P00747 | 1/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.63 |
| ▸ | KLK1 | P06870 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29462782 | 1.00 | CES2 (0.68) | CES2CES1LCKPLAUF2 | |
| SCHEMBL26903783 | 1.00 | CES2 (0.68) | CES2CES1LCKPLAUF2 | |
| Hydrochloric Acid SCHEMBL22558829 | 0.98 | CES2 (0.65) | CES2CES1LCKPLAUF2 | |
| Hydrochloric Acid SCHEMBL30932950 | 0.98 | CES2 (0.65) | CES2CES1LCKPLAUF2 | |
| Hydrochloric Acid SCHEMBL8169297 | 0.98 | CES2 (0.65) | CES2CES1LCKPLAUF2 | |
| Hydrochloric Acid SCHEMBL8358165 | 0.98 | CES2 (0.65) | CES2CES1LCKPLAUF2 | |
| Oxalic Acid SCHEMBL8355001 | 0.94 | PLAU (0.62) | CES2CES1LCKPLAUF2 | |
| SCHEMBL607170 | 0.93 | LCK (0.70) | CES2CES1LCKPLAUF2 | |
| SCHEMBL30350858 | 0.93 | LCK (0.70) | CES2CES1LCKPLAUF2 | |
| SCHEMBL30277311 | 0.93 | LCK (0.70) | CES2CES1LCKPLAUF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1990 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| WO-2025057535-A1 | SEPARATION MEMBRANE | 日東電工株式会社 | 2025-03-20 | — | — | WO | claimed |
| WO-2024176130-A1 | TEAD- AND HER2-INHIBITOR COMBINATIONS FOR TREATING CANCER | NOVARTIS AG (CH) | 2024-08-29 | — | — | WO | claimed |
| CN-115381955-B | Use of melanocortin receptor MC5R | 中国科学技术大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117843590-A | 3-amino-4- (piperazin-1-yl) benzamide derivative, pharmaceutical composition containing same, and preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | claimed |
| CN-110278711-B | Tricyclosulfones as rory modulators | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |
| CN-116891472-A | Amide derivative containing imidazole structure, and preparation method and application thereof | 延边大学 | 2023-10-17 | — | — | CN | claimed |
| CN-116375549-A | Method and system for synthesizing amide compound from nitrile compound | 深圳湾实验室 | 2023-07-04 | — | — | CN | claimed |
| CN-116348455-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | claimed |
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | claimed |
| WO-1994021816-A1 | TEST KITS AND METHODS FOR RAPIDLY TESTING FOR CONTAMINATION BY MICROORGANISMS | ENVIROCON INTERNATIONAL INCORPORATED (US) | 1994-09-29 | — | — | WO | claimed |
| US-5120746-A | Inhibit gastric acid secretion | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-06-09 | — | — | US | claimed |
| US-4643849-A | ANTIULCER, ANTISECRETORY AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-02-17 | — | — | US | claimed |
| EP-0069294-B1 | N-SUBSTITUTED 2 METHYLNAPHTHYL AMIDES, PROCESS FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1985-01-02 | — | — | EP | claimed |
| EP-0069294-A1 | N-substituted 2 methylnaphthyl amides, process for their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1983-01-12 | — | — | EP | claimed |
| EP-0009933-B1 | AROMATIC AMIDE PLASTICIZER FOR IONIC POLYMERS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1982-11-17 | — | — | EP | claimed |
| EP-0001617-B1 | DIAZOTYPE MATERIAL | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-22 | — | — | EP | claimed |
| US-4279810-A | Easily split substrates for the quantification of proteases | KABI AB (SE) | 1981-07-21 | — | — | US | claimed |
| US-4229337-A | NEUTRALIZED SULFONATED ELASTOMER; HEAT RESISTANCE; TENSILE STRENGTH | EXXON RESEARCH & ENGINEERING CO. (US) | 1980-10-21 | — | — | US | claimed |
| EP-0009933-A1 | Aromatic amide plasticizer for ionic polymers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1980-04-16 | — | — | EP | claimed |