Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006650 | 0.85 | MAPK1 (0.65) | KMT2AMEN1MAPK1THRBHRH3 | |
| SCHEMBL2873071 | 0.85 | MAPK1 (0.65) | KMT2AMEN1MAPK1THRBHRH3 | |
| SCHEMBL26928833 | 0.85 | ESR2 (0.65) | KMT2AMEN1MAPK1THRBHRH3 | |
| SCHEMBL1193532 | 0.84 | MAPK1 (0.63) | KMT2AMEN1MAPK1THRBPOLB | |
| SCHEMBL14996180 | 0.81 | KMT2A (0.67) | KMT2AMEN1MAPK1POLBHRH3 | |
| SCHEMBL9781751 | 0.80 | HRH3 (0.60) | KMT2AMEN1MAPK1THRBHRH3 | |
| SCHEMBL21255890 | 0.80 | KMT2A (0.66) | KMT2AMEN1MAPK1POLBHRH3 | |
| SCHEMBL21255989 | 0.80 | ESR1 (0.69) | KMT2AMEN1MAPK1THRBHRH3 | |
| SCHEMBL22196923 | 0.80 | KMT2A (0.66) | KMT2AMEN1MAPK1POLBHRH3 | |
| SCHEMBL13580211 | 0.80 | ABHD6 (0.62) | KMT2APOLBNPC1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032385-A1 | Sustainable chemical processes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2007-02-08 | — | — | US | disclosed |