Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GBA1 | P04062 | 3/20 | 0.54 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.52 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.52 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.52 |
| ▸ | GJB2 | P29033 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8370478 | 0.96 | MAPK1 (0.60) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL8370481 | 0.96 | MAPK1 (0.60) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL5678760 | 0.95 | MAPK1 (0.58) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL25414516 | 0.94 | MAPK1 (0.60) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL25415166 | 0.94 | MAPK1 (0.60) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL25415432 | 0.94 | MAPK1 (0.60) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL14747620 | 0.90 | MAPK1 (0.52) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL21080979 | 0.90 | MAPK1 (0.54) | MAPK1GBA1LGALS8LGALS3LGALS4 | |
| SCHEMBL16678936 | 0.89 | MAPK1 (0.64) | MAPK1LGALS8LGALS3LGALS4GJB2 | |
| SCHEMBL14691296 | 0.89 | MAPK1 (0.64) | MAPK1LGALS8LGALS3LGALS4GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110722-B2 | Aromatic acyltransferase genes | LOCAL INDEPENDENT ADMINISTRATIVE INSTITUTION AOMORI PREFECTURAL INDUSTRIAL TECHNOLOGY RESEARCH CENTER (JP) | 2012-02-07 | — | — | US | disclosed |
| EP-1947179-B1 | NOVEL AROMATIC ACYL GROUP TRANSFERASE GENES | LOCAL INDEPENDENT ADMINISTRATIVE INSTITUTION AOMORI PREFECTURAL IND TECHNOLOGY RES CT (JP) | 2011-09-21 | — | — | EP | disclosed |
| US-20090288225-A1 | Novel Aromatic Acyltransferase Genes | AOMORI PREFECTURE (JP) | 2009-11-19 | — | — | US | disclosed |
| EP-1947179-A1 | NOVEL AROMATIC ACYL GROUP TRANSFERASE GENE | Aomori prefecture (JP) | 2008-07-23 | — | — | EP | disclosed |