SCHEMBL546884

SCHEMBL546884

CCOC(=O)C(c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.54
MAPK1 P28482 5/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 4/20 0.52
LMNA P02545 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 6/20 0.50
GAA P10253 1/20 0.50
MITF O75030 1/20 0.48
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
MEN1 O00255 2/20 0.46
NPC1 O15118 1/20 0.46
MTOR P42345 1/20 0.46
RAB9A P51151 1/20 0.46
CYP1A2 P05177 1/20 0.46
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30080552 1.00 MAPT (0.54) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL31715257 0.95 MAPT (0.50) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL8443380 0.89 MAPT (0.54) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL8878469 0.86 MAPT (0.52) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL11577833 0.85 ALDH1A1 (0.50) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL492620 0.85 MAPT (0.54) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL17701280 0.84 TDP1 (0.56) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL31462828 0.84 TDP1 (0.56) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL11664242 0.82 TDP1 (0.46) MAPTMAPK1SMN1; SMN2TDP1KMT2A
SCHEMBL27987013 0.81 ALDH1A1 (0.63) MAPTSMN1; SMN2KMT2ALMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028877-A1 WATER-INDICATING PASTE COMPOSITIONS ARKEMA FRANCE (FR) 2023-01-26 US claimed
WO-2021130536-A1 WATER-INDICATING PASTE COMPOSITIONS ARKEMA FRANCE (FR) 2021-07-01 WO claimed
EP-3177250-A1 WETNESS INDICATOR WITH PERMANENT COLORANT The Procter and Gamble Company (US) 2017-06-14 EP claimed
WO-2016022795-A1 WETNESS INDICATOR WITH PERMANENT COLORANT THE PROCTER & GAMBLE COMPANY (US) 2016-02-11 WO claimed
US-20160038628-A1 WETNESS INDICATOR WITH PERMANENT COLORANT THE PROCTER & GAMBLE COMPANY 2016-02-11 US claimed
EP-2920254-A1 COMPOSITIONS FOR GENERATING ON-DEMAND DRY-ERASE WRITING SURFACES, FLUID APPLICATORS CONTAINING SAME, AND METHODS Sanford, L.P. (US) 2015-09-23 EP claimed
US-20140186531-A1 Compositions For Generating On-Demand Dry-Erase Writing Surfaces, Fluid Applicators Containing Same, And Methods SANFORD, L.P. (US) 2014-07-03 US claimed
WO-2014106241-A1 COMPOSITIONS FOR GENERATING ON-DEMAND DRY-ERASE WRITING SURFACES, FLUID APPLICATORS CONTAINING SAME, AND METHODS SANFORD, L.P. (US) 2014-07-03 WO claimed
EP-1778801-B1 DECODER SYSTEM SANFORD LP (US) 2013-05-15 EP claimed
US-8110615-B2 Correction fluids SANFORD, L.P. (US) 2012-02-07 US claimed
US-5143023-A Animal litter with chemically bound chemical indicators KLEANHEART, INC. (US) 1992-09-01 US claimed
US-4717671-A INDICATOR DYE, INORGANIC BASE IN A LIQUID CARRIER, GELLING AGENT, BORON COMPOUND PONY INDUSTRIES, INC. (US) 1988-01-05 US claimed
US-4699885-A PASTE INCLUDING INDICATOR DYE PONY INDUSTRIES, INC., A CORP. OF DE 1987-10-13 US claimed
EP-0184062-A2 Personal liquid chemical agent detector ENVIRONMENTAL TECHNOLOGIES GROUP, INC. (US) 1986-06-11 EP claimed
US-4578357-A INDICATOR DYE, INORGANIC BASE, AND BORON CONTAINING, COMPOUND FOR MEASURING WATER LEVEL IN TANKS ATLANTIC RICHFIELD COMPANY (US) 1986-03-25 US claimed
EP-0130675-A2 Chemical composition for the detection of water and probe containing it SARTOMER COMPANY, INC. (US) 1985-01-09 EP claimed
US-4322466-A Sheet printed with invisible inks LOCKLEY SERVICES PTY. LTD. (AU) 1982-03-30 US claimed
US-4113282-A TETRANITRODIPHENYL ACETIC ACID DERIVATIVES THE MEAD CORPORATION (US) 1978-09-12 US claimed
US-3996052-A Phototropic compounds as acid catalyst in photopolymerizing process AMERICAN CAN COMPANY (US) 1976-12-07 US claimed
US-3949143-A Epoxy resin coatings cured with phototropic aromatic nitro compounds AMERICAN CAN COMPANY (US) 1976-04-06 US claimed