⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4492294 | 1.00 | — | — | |
| SCHEMBL18474377 | 1.00 | — | — | |
| Phosphine SCHEMBL27998527 | 0.98 | NOS2 (0.50) | — | |
| Methane SCHEMBL27493565 | 0.98 | NOS2 (0.50) | — | |
| Hydrochloric Acid SCHEMBL5418246 | 0.98 | NOS2 (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL27413104 | 0.98 | NOS2 (0.50) | — | |
| SCHEMBL840224 | 0.98 | NOS2 (0.50) | — | |
| Ethane SCHEMBL27994756 | 0.96 | NOS2 (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL28000860 | 0.96 | NOS2 (0.48) | — | |
| Ammonia Solution, Strong SCHEMBL28838077 | 0.96 | NOS2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4291556-A1 | HYDROXYHETEROCYCLOALKANE-CARBAMOYL DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2023-12-20 | — | — | EP | claimed |
| EP-4237419-A1 | GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1 -CARBAMOYL DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2023-09-06 | — | — | EP | claimed |
| US-20220402983-A1 | PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES | JANSSEN BIOTECH, INC. | 2022-12-22 | — | — | US | claimed |
| WO-2022171594-A1 | HYDROXYHETEROCYCLOALKANE-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-08-18 | — | — | WO | claimed |
| EP-4013751-A1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | Idorsia Pharmaceuticals Ltd (CH) | 2022-06-22 | — | — | EP | claimed |
| WO-2022090544-A1 | GALECTIN-3 INHIBITING 2-HYDROXYCYCLOALKANE-1 -CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-05-05 | — | — | WO | claimed |
| CN-114269737-A | 2-hydroxycycloalkane-1-carbamoyl derivatives | 爱杜西亚药品有限公司 | 2022-04-01 | — | — | CN | claimed |
| US-20210361642-A1 | WASP-PROTECTING SMALL MOLECULES, COMPOSITIONS, METHODS AND USES THEREOF IN THE TREATMENT OF INNATE AND ACQUIRED IMMUNE-RELATED DISORDERS OR CONDITIONS | BAR ILAN UNIVERSITY (IL) | 2021-11-25 | — | — | US | claimed |
| CN-108047157-A | The method of one-step synthesis 2- amino benzoxazoles heterocyclic compounds | 江苏欣诺科催化剂有限公司 | 2018-05-18 | — | — | CN | claimed |
| CN-107382808-A | The preparation method of aza cyclo-butanone derivatives | 凯莱英医药化学（阜新）技术有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-1425297-A | Nicosulfuron herbicide composition | MA YUNSHENG (CN) | 2003-06-25 | — | — | CN | claimed |
| CN-1361776-A | Fluorinated imidazoline benzodioxans, their preparation and their therapeutic use | PF MEDICAMENT (FR) | 2002-07-31 | — | — | CN | claimed |
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | claimed |
| EP-1126833-A2 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2001-08-29 | — | — | EP | claimed |
| CN-1294519-A | Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient | INPHARMA SA (CH) | 2001-05-09 | — | — | CN | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | claimed |
| WO-2000025768-A1 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES, INC. (US) | 2000-05-11 | — | — | WO | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |