Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.75 |
| ▸ | RAB9A | P51151 | 6/20 | 0.75 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469266 | 1.00 | EPHX1 (0.75) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10825858 | 0.94 | EPHX1 (0.83) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL15263046 | 0.94 | EPHX1 (0.83) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL13949482 | 0.88 | EPHX1 (0.73) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL4266974 | 0.88 | EPHX1 (0.73) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28218814 | 0.87 | EPHX1 (0.90) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2752734 | 0.87 | RAB9A (0.96) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL23573481 | 0.86 | EPHX1 (0.77) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL584079 | 0.86 | EPHX1 (0.71) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL584080 | 0.86 | EPHX1 (0.71) | EPHX1RAB9AEPHX2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070135387-A1 | Inhibitors of protein kinases | ABBOTT LABORATORIES | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135387-A1 | Inhibitors of protein kinases | MAP3K20, PACSIN2, MAP4K2 | EPHX1 3225/4885RAB9A 2192/4885EPHX2 3884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.