Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13095176 | 0.85 | HRH1 (0.44) | HRH1CHRNA7ALDH1A1L3MBTL1LOXL2 | |
| SCHEMBL3078710 | 0.77 | HTR2A (0.39) | HRH1CHRNA7ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3888983 | 0.72 | HRH1 (0.47) | HRH1CHRNA7ALDH1A1L3MBTL1LOXL2 | |
| SCHEMBL28126688 | 0.72 | HRH1 (0.47) | HRH1CHRNA7ALDH1A1L3MBTL1LOXL2 | |
| SCHEMBL8346110 | 0.72 | HRH1 (0.47) | HRH1CHRNA7ALDH1A1L3MBTL1LOXL2 | |
| SCHEMBL3082743 | 0.71 | HRH1 (0.46) | HRH1CHRNA7HRH4HRH3CYP2A6 | |
| SCHEMBL3068254 | 0.71 | HRH1 (0.45) | HRH1CHRNA7ALDH1A1L3MBTL1LOXL2 | |
| SCHEMBL30839509 | 0.71 | NOS3 (0.48) | HRH1CHRNA7ALDH1A1L3MBTL1HRH2 | |
| SCHEMBL701433 | 0.71 | NOS3 (0.48) | HRH1CHRNA7ALDH1A1L3MBTL1HRH2 | |
| Hydrochloric Acid SCHEMBL30818111 | 0.69 | TAAR1 (0.47) | HRH1CHRNA7ALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148721-A1 | Compositions, methods, systems, and kits for affinity purification | AGILENT TECHNOLOGIES, INC. (US) | 2007-06-28 | — | — | US | disclosed |