Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.57 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.48 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.48 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.48 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.48 |
| ▸ | CACNG1 | Q06432 | 2/20 | 0.48 |
| ▸ | CACNB2 | Q08289 | 2/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | CACNA1E | Q15878 | 2/20 | 0.48 |
| ▸ | CACNA2D4 | Q7Z3S7 | 2/20 | 0.48 |
| ▸ | CACNA2D3 | Q8IZS8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462079 | 0.93 | HCRTR2 (0.52) | GPR119PDE10AHCRTR2 | |
| SCHEMBL20989499 | 0.82 | GPR119 (0.48) | GPR119PDE10AHCRTR2 | |
| SCHEMBL24289162 | 0.81 | GPR119 (0.51) | GPR119PDE10ABACE1 | |
| SCHEMBL21607055 | 0.81 | GPR119 (0.67) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL5265313 | 0.81 | GPR119 (0.56) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL5274325 | 0.81 | GPR119 (0.59) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL8481341 | 0.81 | GPR119 (0.52) | GPR119PDE10ABACE1 | |
| SCHEMBL18318467 | 0.80 | GPR119 (0.55) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL17973890 | 0.80 | GPR119 (0.58) | GPR119CACNB4CACNA1ACACNA1GCACNG3 | |
| SCHEMBL4269162 | 0.80 | GPR119 (0.55) | GPR119CACNB4CACNA1ACACNA1GCACNG3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021404-A1 | Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | NEUROSEARCH A/S (DK) | 2007-01-25 | — | — | US | disclosed |
| WO-2004113297-A9 | AZA-RING DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021404-A1 | Novel aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | GPR119 164/4885CACNB4 1243/4885CACNA1A 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.