Ethylene Glycol

Ethylene Glycol

SCHEMBL5469504

C=C(CC)C(=O)OCCCCCC.OCCO.OCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.62
NAAA Q02083 1/20 0.53
RAD52 P43351 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
EPHX1 P07099 1/20 0.46
ACHE P22303 7/20 0.44
HCAR2 Q8TDS4 1/20 0.42
MEN1 O00255 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.41
FAAH O00519 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478136 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL3476008 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL375249 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL11803516 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL3627611 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL26413 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL3503795 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL374874 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL3503962 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1
SCHEMBL375676 0.94 TSHR (0.69) TSHRNAAARAD52NPSR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225184-A1 Triarylsilyl(meth)acryloyl-containing polymers for marine coating compositions ARKEMA INC. 2003-12-04 US claimed
US-20070043205-A1 Radiation curable thiol-ene composition DSM IP ASSETS B.V. (NL) 2007-02-22 US disclosed
EP-1622963-A2 RADIATION CURABLE THIOL-ENE COMPOSITION DSM IP Assets B.V. (NL) 2006-02-08 EP disclosed
WO-2004101649-A2 RADIATION CURABLE THIOL-ENE COMPOSITION DSM IP ASSETS B.V. (NL) 2004-11-25 WO disclosed
EP-1477511-A1 Radiation curable thiol-ene composition DSM IP Assets B.V. (NL) 2004-11-17 EP disclosed