Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.74 |
| ▸ | MMP9 | P14780 | 2/20 | 0.68 |
| ▸ | FLT3 | P36888 | 2/20 | 0.66 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.66 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP3 | P08254 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | BACE1 | P56817 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acacetin SCHEMBL891690 | 0.93 | MMP9 (0.71) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Naringenin SCHEMBL28072458 | 0.88 | BACE1 (0.70) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Naringenin SCHEMBL6073059 | 0.88 | BACE1 (0.70) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Naringenin SCHEMBL28072460 | 0.88 | BACE1 (0.70) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Homoeriodictyol SCHEMBL17651827 | 0.86 | MMP9 (0.72) | CYP19A1MAPTTDP1ALDH1A1ATM | |
| Sakuranetin SCHEMBL555541 | 0.86 | CYP19A1 (1.00) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Sakuranetin SCHEMBL555542 | 0.86 | CYP19A1 (1.00) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Sakuranetin SCHEMBL29928748 | 0.86 | CYP19A1 (1.00) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| Sakuranetin SCHEMBL14410473 | 0.86 | CYP19A1 (1.00) | CYP19A1MAPTTDP1ALDH1A1ADORA3 | |
| SCHEMBL16710297 | 0.81 | CYP19A1 (0.90) | CYP19A1MAPTTDP1ALDH1A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299018-A1 | Derivatives of Genkwanin and Sakuranetin, Cosmetic and Therapeutic Use Thereof and Preparation Method of Same | PROST MICHEL | 2007-12-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299018-A1 | Derivatives of Genkwanin and Sakuranetin, Cosmetic and Therapeutic Use Thereof and Preparation Method of Same | GLA, OGA, UGCG | CYP19A1 180/4885MAPT 4503/4885TDP1 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.