SCHEMBL5470276

SCHEMBL5470276

Brc1cc2c3c(c1)CCCN3CCC2

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.55
RXFP1 Q9HBX9 2/20 0.55
RAD52 P43351 1/20 0.55
HTR2C P28335 3/20 0.42
MEN1 O00255 5/20 0.39
USP2 O75604 5/20 0.39
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 4/20 0.39
TDP1 Q9NUW8 4/20 0.39
GAA P10253 3/20 0.39
RECQL P46063 3/20 0.39
HPGD P15428 3/20 0.39
LMNA P02545 3/20 0.39
HSD17B10 Q99714 2/20 0.39
POLB P06746 2/20 0.39
BLM P54132 2/20 0.39
PABPC1 P11940 1/20 0.39
ALOX15 P16050 1/20 0.39
NR4A1 P22736 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL11364490 0.98 KMT2A (0.53) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL2346449 0.96 KMT2A (0.52) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL11223239 0.81 KMT2A (0.59) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL15721662 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL10411260 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL20115140 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL2269084 0.77 KMT2A (0.60) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL1105731 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL11507401 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1
SCHEMBL13503134 0.77 KMT2A (0.55) KMT2ARXFP1RAD52HTR2CMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562817-B1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NAT RECH SCIENT (FR) 2023-11-15 EP disclosed
WO-2018122359-A1 ORGANIC MATERIALS WITH SPECIAL OPTICAL EFFECTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2018-07-05 WO disclosed
US-9960294-B2 Highly fluorescent and photo-stable chromophores for wavelength conversion NITTO DENKO CORPORATION (JP) 2018-05-01 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed
US-20150340519-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2015-11-26 US disclosed
WO-2014107606-A2 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR WAVELENGTH CONVERSION NITTO DENKO CORPORATION (JP) 2014-07-10 WO disclosed
US-7264891-B2 Organic electroluminescent device and organic electroluminescent compound thereof RIT DISPLAY CORPORATION (TW) 2007-09-04 US disclosed
US-20040131885-A1 Organic electroluminescent device and organic electroluminescent compound thereof RITDISPLAY CORPORATION (TW) 2004-07-08 US disclosed
US-4283537-A Thiazine-1,1-dioxide and isothiazole-1,1-dioxide derivatives and process for preparation POLAROID CORPORATION (US) 1981-08-11 US disclosed
US-4259493-A INDICATOR DYES OR PHOTOGRAPHIC LIGHT-SCREENING DYES POLAROID CORPORATION (US) 1981-03-31 US disclosed
US-4255578-A Synthesis of perhalomethylcarbinol-substituted phenol and naphthol sulfamphthalein dyes from the corresponding triacylated derivatives POLAROID CORPORATION (US) 1981-03-10 US disclosed
US-4210752-A Synthesis of substituted sulfam(na)phthaleins POLAROID CORPORATION (US) 1980-07-01 US disclosed
US-4186001-A IRREVERSIBLE CLEAVAGE IN ALKALINE SOLUTION TO FORM COLORLESS COMPOUND POLAROID CORPORATION (US) 1980-01-29 US disclosed
US-4178447-A Novel synthesis of 3,3-substituted dihydrobenzisothiazole-1,1-dioxides and -2,3-dihydronaphtho-1,2-thiazine-1,1-dioxides POLAROID CORPORATION (US) 1979-12-11 US disclosed
US-4140689-A 3-(Julolidinyl)-benz[d]isothiazole-1,1-dioxide POLAROID CORPORATION (US) 1979-02-20 US disclosed