Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 1.00 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.53 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14463980 | 0.86 | TACR1 (1.00) | TACR1 | |
| SCHEMBL8786435 | 0.81 | TACR1 (0.73) | TACR1SGMS1SGMS2 | |
| SCHEMBL8784841 | 0.76 | TACR1 (1.00) | TACR1 | |
| SCHEMBL9059887 | 0.76 | TACR1 (0.62) | TACR1 | |
| SCHEMBL5331418 | 0.76 | TACR1 (0.80) | TACR1 | |
| SCHEMBL8786183 | 0.74 | TACR1 (0.78) | TACR1 | |
| SCHEMBL8786688 | 0.74 | TACR1 (0.77) | TACR1 | |
| SCHEMBL8786442 | 0.74 | TACR1 (0.77) | TACR1 | |
| SCHEMBL8784772 | 0.74 | TACR1 (0.65) | TACR1 | |
| SCHEMBL8786174 | 0.74 | TACR1 (0.65) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074491-A1 | HETEROTRICYCLIC AMIDE DERIVATIVES AS NEUROKININ-l (NKl) RECEPTOR LIGANDS | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2007-07-05 | — | — | WO | disclosed |