SCHEMBL547104

SCHEMBL547104

CCCCCCCCc1c(CCC(=O)O)cc(-n2nc3ccccc3n2)c(O)c1C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
CYSLTR2 Q9NS75 6/20 0.36
CYSLTR1 Q9Y271 6/20 0.36
POLB P06746 2/20 0.36
NR1H4 Q96RI1 1/20 0.35
OXER1 Q8TDS5 5/20 0.35
HTT P42858 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
GAA P10253 1/20 0.34
PTGES O14684 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721171 0.92 CYSLTR2 (0.36) NPC1RAB9ACYSLTR2CYSLTR1POLB
SCHEMBL8640100 0.84 NR1H4 (0.42) NPC1RAB9APOLBNR1H4KDM4E
SCHEMBL7160541 0.82 F2R (0.38) CYSLTR2CYSLTR1POLBOXER1HTT
SCHEMBL817511 0.78 NPSR1 (0.39) NR1H4ALDH1A1GAA
SCHEMBL11366464 0.78 NPSR1 (0.39) NR1H4ALDH1A1GAA
SCHEMBL251685 0.78 NPSR1 (0.39) NR1H4ALDH1A1GAA
SCHEMBL30698057 0.76 CYSLTR2 (0.39) NPC1RAB9ACYSLTR2CYSLTR1OXER1
SCHEMBL27540134 0.76 NPC1 (0.43) NPC1RAB9ACYSLTR2CYSLTR1POLB
SCHEMBL8362661 0.76 NR1H4 (0.44) NPC1RAB9APOLBNR1H4KDM4E
SCHEMBL21192206 0.74 HTT (0.39) NPC1RAB9ACYSLTR2CYSLTR1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2188669-B1 ELECTROFLUIDIC DEVICES, VISUAL DISPLAYS, AND METHODS FOR MAKING AND OPERATING SUCH ELECTROFLUIDIC DEVICES UNIV CINCINNATI (US) 2017-01-11 EP disclosed
US-8730154-B2 Display apparatus GAMMA DYNAMICS LLC (US) 2014-05-20 US disclosed
US-20130033476-A1 DISPLAY APPARATUS DEAN KENNETH A (US) 2013-02-07 US disclosed
US-8111465-B2 Electrofluidic devices, visual displays, and methods for making and operating such electrofluidic devices UNIVERSITY OF CINCINNATI (US) 2012-02-07 US disclosed
US-20100208328-A1 Electrofluidic Devices, Visual Displays, And Methods For Making And Operating Such Elecrofluidic Devices UNIVERSITY OF CINCINNATI (US) 2010-08-19 US disclosed
EP-2188669-A1 ELECTROFLUIDIC DEVICES, VISUAL DISPLAYS, AND METHODS FOR MAKING AND OPERATING SUCH ELECTROFLUIDIC DEVICES University of Cincinnati (US) 2010-05-26 EP disclosed
WO-2009036272-A1 ELECTROFLUIDIC DEVICES, VISUAL DISPLAYS, AND METHODS FOR MAKING AND OPERATING SUCH ELECTROFLUIDIC DEVICES UNIVERSITY OF CINCINNATI (US) 2009-03-19 WO disclosed
US-20090062171-A1 Home or fabric care compositions comprising certain dye-polymer complexes BASF SE (DE) 2009-03-05 US disclosed
US-6416627-B1 PENDANT NITROXIDE, HYDROXYLAMINE OR HYDROXY-AMMONIUM SALT GROUPS, WATER SOLUBLE OR WATER DISPERSIBLE; PREVENT THE LOSS OF BRIGHTNESS AND ENHANCE RESISTANCE TO YELLOWING CIBA SPECIALTY CHEMICALS CORPORATION 2002-07-09 US disclosed