Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | RXRB | P28702 | 2/20 | 0.34 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547104 | 0.84 | NPC1 (0.37) | NR1H4NPC1RAB9APOLBLMNA | |
| SCHEMBL8362661 | 0.84 | NR1H4 (0.44) | NR1H4NPC1RAB9APOLBLMNA | |
| SCHEMBL29721171 | 0.80 | CYSLTR2 (0.36) | NR1H4NPC1RAB9APOLBLMNA | |
| SCHEMBL8835025 | 0.80 | NR1H4 (0.37) | NR1H4NPC1RAB9APOLBPPARG | |
| SCHEMBL7696202 | 0.77 | NPC1 (0.40) | NR1H4NPC1RAB9APOLBLMNA | |
| SCHEMBL29768287 | 0.77 | MAOB (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL100766 | 0.77 | MAOB (0.45) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL2045035 | 0.76 | NPC1 (0.50) | NPC1RAB9APOLBLMNAPPARG | |
| SCHEMBL28881625 | 0.76 | NPC1 (0.42) | NPC1RAB9APOLBLMNAPPARG | |
| SCHEMBL30440369 | 0.75 | NPC1 (0.46) | NPC1RAB9APOLBLMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821554-A | REACTING TEREPHTHALIC ACID AND ADIPIC ACID WITH POLYHYDRIC ALCOHOL, REACTING PRODUCT WITH POLYISOCYANATE; LOW DENSITY, HIGH TENSILE STRENGTH FOAM | KAO CORPORATION (JP) | 1998-10-13 | — | — | US | disclosed |
| US-5739377-A | STABILIZER FOR POLYMERS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |