SCHEMBL5472008

SCHEMBL5472008

CCOC(=O)C(C)(C)Oc1c(C)cc(CN(CC(=O)NCC(C)=O)C(=O)OCC2c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FSHR P23945 1/20 0.33
KMT2A Q03164 2/20 0.32
PPARA Q07869 2/20 0.32
PPARG P37231 1/20 0.32
EPHX2 P34913 1/20 0.31
OPRD1 P41143 1/20 0.30
TLR7 Q9NYK1 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5481185 0.90 KMT2A (0.37) FSHRKMT2APPARAPPARGEPHX2
SCHEMBL5480676 0.89 KMT2A (0.32) FSHRKMT2APPARAPPARG
SCHEMBL5481577 0.88 PPARA (0.35) KMT2APPARAPPARGEPHX2TLR7
SCHEMBL5477221 0.87 PPARA (0.34) KMT2APPARAPPARGEPHX2
SCHEMBL5472110 0.80 PPARA (0.33) PPARAPPARG
SCHEMBL5482666 0.79 PPARA (0.33) PPARAPPARG
SCHEMBL5484449 0.72 PPARA (0.41) PPARAPPARGTLR7
SCHEMBL5479996 0.71 PPARA (0.39) PPARAPPARGTLR7
SCHEMBL5477030 0.71 PPARA (0.40) PPARAPPARGTLR7
SCHEMBL21689327 0.65 KMT2A (0.55) KMT2AEPHX2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD FSHR 194/4885KMT2A 1816/4885PPARA 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.